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KMID : 1137820120330040202
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의공학회지
2012 Volume.33 No. 4 p.202 ~ p.206
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Development of Micro-needle Device for Direct Drug Delivery into the Dermis
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Eum Nyeon-Sik
Kim Hyung-Kyung
Han Jung-Hyun
Kim Su-Jeong
Park Hee-Joon
Kang Shin-Won
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Abstract
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In this study, we developed transdermal direct drug delivery device using micro-needle painlessly. We has fabricated micro-needle that is 130 thickness and 250 length with 10 spiral groove for rolling down drug. Head part of micro-needle device is composed of 20ea micro-needles, an on-off valve and a protective cap. Glass bottle for containing drug is connected to head part of micro-needle device. We examined the puncture characteristic testing using porcine skin and drug delivery testing using porcine, rat skin with Indian Ink.
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KEYWORD
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Acupuncture Micro Needle, Direct Drug Delivery, Derma, Stimulator
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